Congenital
The kind of GH that some babies are born with, even though they may appear to be growing normally until about 6 to 12 months old.
About Pediatric GHD
Understanding the Science
The Science Behind Growth Hormone Deficiency (GHD)
GHD is a condition characterized by an insufficient production or secretion of growth hormone (GH) by the pituitary gland, a small gland located at the base of the brain. GH plays a crucial role in stimulating growth, particularly in bones and muscles. The science behind GHD involves understanding the causes, effects, and mechanisms involved.
Here are key aspects of the science behind GHD:
1
Pituitary Gland Dysfunction
Most cases of GHD are associated with dysfunction or abnormalities in the pituitary gland. The pituitary gland is responsible for producing and releasing various hormones, including GH.
2
The impact of GH function on the body
In the bloodstream, GH impacts various bodily systems to promote growth in children. However, once the growth plates in their bones have closed, GH ceases to stimulate height increase. Nevertheless, the body continues to require GH for maintaining normal body structure and metabolism. After bones stop growing in length, GH plays a crucial role in regulating body composition and ensuring metabolic balance.
3
There are various types of Growth Hormone Deficiency
Acquired
Occurs when damage to the pituitary gland leads to the onset of GHD after birth, which can happen at any age, including during childhood. This condition results from various factors that disrupt normal pituitary function.
Idiopathic
This means there is no identifiable cause for the growth hormone deficiency.
4
Genetic Factors
In some cases, GHD can result from genetic mutations or abnormalities that affect the production, secretion, or action of GH.
The classification of GHD can be complex, and the underlying causes can vary widely. Additionally, the severity of the deficiency can range from mild to severe. A thorough evaluation by healthcare professionals, including a pediatric endocrinologist, is necessary to determine the type, cause, and appropriate treatment for GHD.
Test Your Knowledge
This site aims to provide comprehensive information on the identification, diagnosis, and treatment of growth hormone deficiency (GHD). Take the quiz to test your knowledge.
QUESTION 1 of 8
What is the prevalence of GHD in children?
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What are some of the symptoms children with GHD may experience?
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Once growth hormone (GH) is in the blood, it increases production of what other hormone?
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GH is important for what?
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GH is produced in what gland?
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Diagnosis of GH in children may include what type of testing?
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Treatments for GH deficiency may involve taking?
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What do you call a doctor who specializes in growth-related disorders in children?
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Test Your Knowledge
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